Tabletop Vial, Syringe & Cartridge Filling Machine

AST's Container Filling System (CFS) is a bench top, semi-automatic filling machine used for filling a variety of pharmaceutical containers including vials, syringes, and cartridges. The system’s flexibility allows processing of a wide range of pharmaceutical containers. With a compact design and easy to use functions, the system is completely compatible with hydrogen peroxide isolator bio-decontamination, and can be manually cleaned using common reagents like isopropyl alcohol and sporicides. The Container Filling System's versatility, features, and compact size makes it ideally suited for labs and cGMP environments for filling of small batch pharmaceutical products.

Container Filling Process

AST has constructed an industry leading benchtop filling machine that is easy to use, precise and accurate. The vial, syringe, or cartridge is manually placed on the machine by the operator where they will then position the container. Once the containers are positioned appropriately, the machine begins the filling process by placing the needle within the container and initiates the filling cycle with the peristaltic pump. During the filling cycle the filling needle slowly lifts to maintain a set distance between the tip of the filling needle and the liquid line to minimize shear, foaming or agitation of the dispensed material. For applications in which peristaltic pumps are not ideal, such as dispensing viscous materials, the system can be configured with alternative options like a rotary piston pump.

Advanced Filling Features

  • High-resolution touchscreen interface to create unique recipes and to control the machine.
  • Motion Control System to position the filling needed within the container and slowly retracts as required during the filling cycle to minimize foaming, agitation, and splashing of the dispensed material.
  • Integrated Peristaltic Pump gently and accurately fills the container with a pre-sterilized single-use fluid path.
  • Integrated In-process Control (IPC) dispensing system automatically weighs the dispensed volume into the container to ensure that the containers being filled are within tightly controlled recipe parameters.
  • Compact Design makes it well suited for aseptic environments provides by isolators, biological safety cabinets or laminar air flow (LAF) hoods.

Small Batch Processing Capabilities

The Container Filling System provides complete and precise control of the container filling functions to ensure a consistent and repeatable filling process. Changing the system to process different containers is easy, and can be done in minutes without tools by changing only a few parts. By rapidly changing the system it can be quickly configured for your next batch.

Benefits

  • Accurate & gentle peristaltic dipensing
  • Simple format change-over
  • Programmable filling needle motion
  • Optional weigh cell integration for automated pump calibration
  • Compact system footprint allows for placement with an isolator, biological safety cabinet or LAF
  • Can be configured with multiple pump options including rotary piston
  • Capable of inert gas purging during filling

Versatile & Compact Semi-Automatic filling machine for vials, syringes & Cartridges

Ideal for small batches in laboratory or cGMP settings

Accurate dispensing and filling cycles

Advanced control system with a touchscreen and batch reports

Manual cleaning capabilities with reagents such as isopropyl and sporicides

 

Coming Soon

Technical Information

Dimensions (LxWxH):

725mm x 500mm x 630mm

Containers:

Vials, Syringes & Cartridges

Vial Finish:

13mm, 20mm, 32mm

Vials Sizes (Dia./Height):

Ø16mm-47mm / 35mm-100mm

Syringe Sizes:

0.5mL - 20mL

Cartridge Sizes:

1-5mL (pre-capped or pre-plungered)

Production Rate:

Up to 15 cycles per minute

Fill Accuracy:

Up to +/-0.5%

Electrical Utilities:

110/220VAC – 60/50Hz.

Materials of Construction:

Pharmaceutical grade stainless steels and plastics

Available Options:

  • In-process fill wieght verification (IPC)
  • Rotary piston pump
  • Inert gas overlay
  • Batch reporting
  • Single-use disposable fluid paths
  • Product bag support stand

*Figures are typical.  Actual performance results vary depending upon application requirements.

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