PRODUCTS

Semi-Automatic Vial Sealing for Small-Scale Processing

AST’s Vial Sealing System (VSS) is a benchtop, semi-automatic machine used for sealing or capping pharmaceutical vials and bottles with aluminum caps. The VSS provides complete and precise control of the container sealing or capping operations to ensure the highest quality vial seal. The system’s versatility allows for the processing of a wide range of vial or bottle sizes and finishes and is ideal for small batch processing of sterile pharmaceutical and biotechnology products.

The Vial Sealing System was designed with cGMP in mind. Its compact, aseptic design provides complete compatibility with cleanrooms, bio-safety cabinets, laminar airflow hoods, and aseptic isolator environments.

In the Know

Aesthetic, Pharmaceutical-Grade Sealing for Vials and Bottles

Proper application of the vial cap is critical to container closure integrity, sterility and stability of the drug product within the vial. The Vial Sealing System monitors critical parameters such as applied force prior to forming the seal on the aluminum skirt to ensure proper stopper compression during the sealing process. The system utilizes a free-spinning disk design that has been optimized to minimize the generation of particles during the sealing process and to form a pharmaceutically aesthetic seal.

VSS highlights:

  • Lower particle generation when compared to traditional crimping
  • Processes wide range of vial sizes and diameters
  • Intuitive interface for easy system operation
  • Consistent high-quality vial seals
  • Ability to process wide range of vial sizes and finishes
  • Tool-less format change parts
  • Optional Electronic Batch Reporting (EBR) system
  • Compact system footprint allows placement within an isolator, bio-safety cabinet or laminar airflow hood
 

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Meeting Industry Needs

r&s vss
R&D, preclinical and process development
clinical trial materials manufacturing - vss
Clinical trial materials manufacturing
gene & cell therapy - syringes feature
Gene & cell therapies
small batch commercial drug feature
Small batch commercial drug products
stability studies - vss
Stability studies
compounding pharmacy - vss
Compounding pharmacies

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